Clinical aspects of campylobacter jejuni infections in adults


Extra-intestinal illness is well described, most classically with infection has also been strongly associated with a range of post-infectious sequelae, including Guillain-Barre Syndrome (GBS), post-infectious irritable bowel syndrome (IBS), and reactive arthritis. Intranasal immunization with chitosan/p CAGGS-fla A nanoparticles inhibits Campylobacter jejuni in a White Leghorn model. Emergence of Infectious Diseases into the 21st Century, 2008. John Mc Fadyean and the Centenary of the First Isolation of Campylobacter Species.

GBS associated with is of the acute motor axonal neuropathy variant (171) and occurs following every one in 1,000-5,000 infections (172).

Several enzyme immunoassay (EIA) stool antigen tests have been developed, with early studies showing excellent performance in comparison to culture (181). Septic cavernous sinus thrombosis due to Campylobacter rectus infection.

However, routine use of these tests in clinical microbiology laboratories has revealed a high false-positivity rate (182, 183). Thus a clear understanding of the clinical context is needed to interpret the EIA result.

is considered to be the most common cause of bacterial gastroenteritis worldwide, the single most common inciting agent for Guillain-Barre Syndrome, and an important cause of post-infectious Irritable Bowel Syndrome.